Assessment of Vitamin D3 Level Among a Sample of Type 2 Diabetic Patients Attending Diabetes and Endocrinology Center in Al-Hilla City

Authors

  • Ahmed Mahdi Habeeb College of Health & Medical Technology - Baghdad, Middle Technical University, Baghdad, Iraq
  • Atta Ah Mousa Al-Sarray College of Health & Medical Technology - Baghdad, Middle Technical University, Baghdad, Iraq
  • Ali Hussein Al Hafidh College of Health & Medical Technology - Baghdad, Middle Technical University, Baghdad, Iraq
  • Rafah Sabah Barrak Faculty of Medicine "Ibn El Jazzar" of Sousse, University of Sousse, Sousse, Tunisia
  • Afraa Brahim Faculty of Medicine "Ibn El Jazzar" of Sousse, University of Sousse, Sousse, Tunisia

DOI:

https://doi.org/10.51173/jt.v5i3.1452

Keywords:

Vitamin D3 (Cholecalciferol), T2DM, Educational Level

Abstract

Vitamin D is found in foods in two primary forms: cholecalciferol (vitamin D3) and ergocalciferol (vitamin D2), with vitamin D3 being a fat-soluble vitamin.  that is necessary for calcium homeostasis and the maintenance of proper function in a variety of tissues. Humans get vitamin D from their diets or from being exposed to ultraviolet B radiation from the sun. Aside from its well-known effects on bone health, vitamin D has been hypothesized to play a role in various disease states and health situations, such as cardiovascular disease and type 2 diabetes. To assess vitamin D3 concentration in patients with type 2 diabetes, using the Vitamin D Total III kit on the Cobas E 411 device. A total of 300 people were recruited, with 150 people suffering from type 2 diabetes serving as cases and 150 healthy volunteers of the same gender and age being used as the control group. Both genders were represented, with an age group between 30 – 79 years. The collection of data lasts for five months, beginning Started in November 2022 to April 2023. The data was analyzed with the readily available statistical package SPSS-28, and Chi-square tests were used to evaluate the relationship among vitamin D, T2DM, and control. Data were provided in simple frequency, percentage, mean, standard deviation, and range measures. Type 2 diabetes patients' mean ± SD ages were 55.4 ± 10.1, while controls had a mean ± SD of age of 55.3 ± 10.0. the sociodemographic features of T2DM and participant control. Shows A statistically significant association was found in the variables of age groups, school level (P = 0.0001), and marital status (P = 0.008). The BMI: mean ± SD (29.69 ± 5.14) of T2DM was higher than the BMI: mean ± SD (24.41 ± 1.95) of controls, as well as the waist-to-height ratio, which showed that the mean ± SD (0.527 ± 0.046) of T2DM was greater than the control mean ± SD (0.483 ± 0.019) at level (P = 0.0001); T2DM patients had deficient and insufficient vitamin D3 levels (38.7% and 33.3%, respectively), whereas controls had deficient and insufficient vitamin D3 levels (28.7% and 30.0%, respectively). It was found that there is a significant difference between low vitamin D3 levels and individuals with type 2 diabetes, and A lack of vitamin D3 is related to an increased risk of developing T2DM.

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Author Biographies

Ahmed Mahdi Habeeb, College of Health & Medical Technology - Baghdad, Middle Technical University, Baghdad, Iraq

  

Atta Ah Mousa Al-Sarray, College of Health & Medical Technology - Baghdad, Middle Technical University, Baghdad, Iraq

  

Ali Hussein Al Hafidh, College of Health & Medical Technology - Baghdad, Middle Technical University, Baghdad, Iraq

  

Rafah Sabah Barrak, Faculty of Medicine "Ibn El Jazzar" of Sousse, University of Sousse, Sousse, Tunisia

     

Afraa Brahim, Faculty of Medicine "Ibn El Jazzar" of Sousse, University of Sousse, Sousse, Tunisia

     

References

A. Senyigit, “The association between 25-hydroxy vitamin D deficiency and diabetic complications in patients with type 2 diabetes mellitus,” Diabetes Metab. Syndr. Clin. Res. Rev., vol. 13, no. 2, pp. 1381–1386, 2019, doi: 10.1016/j.dsx.2019.01.043.

E. M. Mikhael, M. A. Hassali, S. A. Hussain, and N. Shawky, “Self-management knowledge and practice of type 2 diabetes mellitus patients in Baghdad, Iraq: A qualitative study,” Diabetes, Metab. Syndr. Obes. Targets Ther., vol. 12, pp. 1–17, 2019, doi: 10.2147/DMSO.S183776.

N. Alcubierre et al., “Vitamin D deficiency is associated with poorer satisfaction with diabetes-related treatment and quality of life in patients with type 2 diabetes,” Health Qual. Life Outcomes, vol. 16, no. 1, pp. 1–8, 2018.

Y. Liang et al., “1,25-Dihydroxy vitamin D3 treatment attenuates osteopenia, and improves bone muscle quality in Goto-Kakizaki type 2 diabetes model rats,” Endocrine, vol. 64, pp. 184–195, 2020, doi: 10.1007/s12020-019-01857-5.

T. S. Vuksanovic and V. Kneževic, “Prevalence of vitamin D3 deficiency in patients with type 2 diabetes and proteinuria,” Vojnosanit. Pregl., vol. 78, no. 12, pp. 1292–1302, 2021, doi: 10.2298/VSP200220064S.

A. G. Pittas et al., “Vitamin D Supplementation and Prevention of Type 2 Diabetes,” N. Engl. J. Med., vol. 381, no. 6, pp. 520–530, 2019, doi: 10.1056/nejmoa1900906.

M. Abusaib et al., “Iraqi Experts Consensus on the Management of Type 2 Diabetes/Prediabetes in Adults,” Clin. Med. Insights Endocrinol. Diabetes, vol. 13, 2020, doi: 10.1177/1179551420942232.

G. E. Fagundes et al., “Vitamin D3 as adjuvant in the treatment of type 2 diabetes mellitus: modulation of genomic and biochemical instability,” Mutagenesis, vol. 34, pp. 135–145, 2019, doi: 10.1093/mutage/gez001.

P. Saeedi et al., “Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9th edition,” Diabetes Res. Clin. Pract., vol. 157, p. 107843, 2019, doi: 10.1016/j.diabres.2019.107843.

S. Wieder-Huszla et al., “Relationships between Vitamin D 3 and Metabolic Syndrome,” 2019, doi: 10.3390/ijerph16020175.

X. Hou et al., “Stronger associations of waist circumference and waist-to-height ratio with diabetes than BMI in Chinese adults,” Diabetes Res. Clin. Pract., vol. 147, pp. 9–18, Jan. 2019, doi: 10.1016/j.diabres.2018.07.029.

B. Angel, L. Lera, C. Márquez, and C. Albala, “The association of VDR polymorphisms and type 2 diabetes in older people living in community in Santiago de Chile,” Nutr. Diabetes, vol. 8, p. 31, 2018, doi: 10.1038/s41387-018-0038-9.

Y. Hao and Y. Chen, “Vitamin D levels and vitamin D receptor variants are associated with chronic heart failure in Chinese patients,” J. Clin. Lab. Anal., vol. 33, no. 4, pp. 1–7, 2019, doi: 10.1002/jcla.22847.

H. I. El Gendy, N. A. Sadik, M. Y. Helmy, and L. A. Rashed, “Vitamin D receptor gene polymorphisms and 25(OH) vitamin D: Lack of association to glycemic control and metabolic parameters in type 2 diabetic Egyptian patients,” J. Clin. Transl. Endocrinol., vol. 15, no. November 2018, pp. 25–29, 2019, doi: 10.1016/j.jcte.2018.11.005.

S. N. Dipti Sarma, Vikram Singh Chauhan, Kandarpa Kumar Saikia1 , Partha Sarma1, “Prevalence Pattern of Key Polymorphisms in the Vitamin D Receptor gene among Patients of Type 2 Diabetes Mellitus in Northeast India,” 2018, doi: 10.4103/ijem.IJEM_213_17.

G. Gembillo et al., “medicina Role of Vitamin D Status in Diabetic Patients with Renal Disease,” Medicina (B. Aires)., vol. 55, p. 273, 2019, doi: 10.3390/medicina55060273.

M. S. Aparna P1, B. Nongkynrih1, and Sanjeev Kumar Gupta1, “Vitamin D deficiency in India,” 2018, doi: 10.4103/jfmpc.jfmpc_78_18.

A. ah mousa alsarray Alaa Mehdi salih, “Practices regarding HPV and cervical cancer in asample of paramedical staff in al Najaf Governorate, Iraq,” J. Tech., vol. 4, no. no., special, pp. 45–51, 2022.

R. haider S. Atta ah mousa alsarray, “awareness of health care provider about CONID-19 vaccination in karbala city,” J. Tech., vol. 4, no. no., special, pp. 91–96, 2022.

Y. Gao et al., “Vitamin D and incidence of prediabetes or type 2 diabetes: A four-year follow-up community-based study,” Dis. Markers, vol. 2018, 2018, doi: 10.1155/2018/1926308.

A. D. Submitted et al., “VITAMIN D STATUS AND GLYCAEMIA IN TYPE 2 DIABETES MELLITUS SUBJECTS IN LAGOS , NIGERIA,” no. November, 2013.

M. ElJilani, H. Alemam, and A. Bashein, “Vitamin D and liver enzymes’ levels in Libyans with type 2 diabetes,” Libyan J. Med. Sci., vol. 5, no. 3, p. 116, 2021, doi: 10.4103/ljms.ljms_18_21.

S. Narayanan and R. Gopikuttan, “The correlation of vitamin D with HOMA-IR and glycated hemoglobin in type 2 diabetes mellitus patients,” Baghdad J. Biochem. Appl. Biol. Sci., vol. 3, no. 04, pp. 273–285, Nov. 2022, doi: 10.47419/bjbabs.v3i04.153.

A. EL Ashiry, M. Gadallah, mohamed mashahit, E. Bayoumy, shahira El-Shafie, and D. Boulos, “Vitamin D status Association with newly diagnosed Type2 Diabetes Mellitus: A Case Control Study,” Fayoum Univ. Med. J., vol. 1, no. 1, pp. 40–48, 2018, doi: 10.21608/fumj.2018.5505.

S. F. Ogail, S. N. Muhsin, and W. I. Abbas, “Evaluation of vitamin D level among patients with type 2 diabetes in Nineveh Governorate-Iraq,” vol. 140, no. 04, pp. 2279–2285, 2022.

M. Khudayar et al., “The Association Between Deficiency of Vitamin D and Diabetes Mellitus Type 2 (DMT2),” Cureus, vol. 2, no. 2, pp. 1–5, 2022, doi: 10.7759/cureus.22221.

A. Anyanwu et al., “Serum Vitamin D Levels in Persons with Type 2 Diabetes Mellitus in Lagos, Nigeria,” Int. J. Diabetes Clin. Res., vol. 7, no. 4, pp. 1–7, 2020, doi: 10.23937/2377-3634/1410133.

M. Shojaei, K. Rahmanian, and A. S. Jahromi, “Relation of type 2 diabetes mellitus with gender, education, and marital status in an Iranian urban population,” Reports Biochem. Mol. Biol., vol. 1, no. 2, 2013, [Online]. Available: www.RBMB.net

A. Aregbesola, S. Voutilainen, J. K. Virtanen, J. Mursu, and T. P. Tuomainen, “Gender difference in type 2 diabetes and the role of body iron stores,” Ann. Clin. Biochem., vol. 54, no. 1, pp. 113–120, 2017, doi: 10.1177/0004563216646397.

W. O. Balogun and O. Gureje, “Self-reported incident type 2 diabetes in the ibadan study of ageing: Relationship with urban residence and socioeconomic status,” Gerontology, vol. 59, no. 1, pp. 3–7, 2012, doi: 10.1159/000340062.

M. Dudzińska et al., “Type 2 diabetes mellitus in relation to place of residence: Evaluation of selected aspects of socio-demographic status, course of diabetes and quality of life - a cross-sectional study,” Ann. Agric. Environ. Med., vol. 20, no. 4, pp. 869–874, 2013.

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Published

2023-09-30

How to Cite

Ahmed Mahdi Habeeb, Atta Ah Mousa Al-Sarray, Ali Hussein Al Hafidh, Rafah Sabah Barrak, & Afraa Brahim. (2023). Assessment of Vitamin D3 Level Among a Sample of Type 2 Diabetic Patients Attending Diabetes and Endocrinology Center in Al-Hilla City. Journal of Techniques, 5(3), 207–212. https://doi.org/10.51173/jt.v5i3.1452

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Medical techniques

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